Search results for: “clinical trials”
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Ocugen Clinical Trial Could Lead to Breakthrough One-Time Treatment for Advanced Dry Macular Degeneration
NORTHAMPTON, Ma., Dec. 19, 2023 — The American Macular Degeneration Foundation received news that the first patient has been dosed in a safety and efficacy clinical trial of a one-time gene therapy treatment for advanced dry macular degeneration (dry AMD), also known as Geographic Atrophy (GA). What’s exciting about this trial is that, if successful,…
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With Gifts From Donors, AMDF Invests In Breakthrough Macular Degeneration Research
As we get ready to turn another year over, we’d like to pause and share a few of the standout highlights and breakthroughs that donor support, your support, helped achieve. In 2024, donor gifts were directed toward multiple research projects, and these investigations continue to evolve toward meaningful improvements in the lives of those affected…
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Research Concludes Macular Degeneration is a Risk Factor for Severe Covid-19
Fairly early in the pandemic, we reported that AMD might be a risk factor for more severe COVID infections. Doctors had observed high rates of severe COVID-19 infections and death among hospitalized patients who had AMD, but the evidence was anecdotal. The most recent research, published by researchers at Boston University Chobanian & Avedisian School of…
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New Treatments for Macular Degeneration on the Horizon
In addition to some exciting new treatments now FDA-approved for the treatment of different stages of macular degeneration (published in the current issue of our print newsletter, In the Spotlight, several new treatment options for macular degeneration are on the horizon. Emerging Approaches to AMD Treatments The process of capturing light and transforming it into…
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Breaking News – FDA Approves First Geographic Atrophy Treatment, SYFOVRE
A groundbreaking, new frontier in macular degeneration treatment has been announced! With the FDA’s approval of Syfovre™, for the first time there’s hope to preserve sight for millions of patients with the advanced stage of dry macular degeneration (dry AMD), called geographic atrophy (GA). “This is extraordinary news,” said Chip Goehring, Founder and President of…
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Geographic Atrophy
Geographic Atrophy (GA), is an advanced form of dry age-related macular degeneration (AMD) that causes cell death (atrophy) in areas of the retina and can lead to irreversible vision loss. It is characterized by large, well-demarcated sections of the retina that stop functioning. A diagnosis of GA must be made by an eye care specialist,…
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Aparna Lakkaraju
Aparna Lakkaraju, PhD, Associate Professor, University of California, San Francisco, School of Medicine Research in the Lakkaraju laboratory builds on fundamental insights from retinal cell biology to develop effective therapies for inherited and age-related macular degeneration (AMD). The initial site of injury in AMD is the retinal pigment epithelium (RPE), the tissue that nourishes and…
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Study Demonstrates Essential Role of Zeaxanthin in Retina Health
Schepens/Harvard study provides direct proof of dietary nutrient’s essential role in protecting the retina from the damaging effects of light Research performed at Schepens Eye Research Institute and Department of Ophthalmology, Harvard Medical School has established that the dietary zeaxanthin (zee-uh-zan’-thin) plays an essential role in protecting the retina of the eye from the damaging…
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Past Research Grants
*This section is still under construction and does not represent the full list 2022 AMDF Research Grants AMDF Breakthrough Award (for Stargardt’s) To Martin-Paul Agbaga, PhD, Assistant Professor, Department of Ophthalmology, University of Oklahoma Health Sciences Center, to optimize and create methods for efficient delivery of very long chain polyunsaturated fatty acids to the retina,…
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Types and Stages of Macular Degeneration
Types of Macular Degeneration There are two types of age-related macular degeneration (AMD), commonly referred to as “dry” or “wet.” They are named for the kinds of physical changes that affect the retina, and in particular the macula, the central area of the retina which gives us our visual acuity, color vision and ability to…